mouse SIRT2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Sirt2.
shAAV-272008
AAV-m-SIRT2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Sirt2 (sirtuin 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
5730427M03Rik; Sir2l; SIR2L2
Description (Vector)
NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and non-histone proteins. Deacetylates 'Lys-40' of alpha-tubulin. Involved in the control of mitotic exit in the cell cycle, probably via its role in the regulation of cytoskeleton. Deacetylates PCK1, opposing proteasomal degradation. Deacetylates 'Lys-310' of RELA.
Gene ID
64383
Gene Name (Vector)
sirtuin 2
Gene Symbol
Sirt2
ORF Size (aa)
1170
ORF Size (bp)
1170 bp
RefSeq ID
NM_022432
RefSeq Synonyms
NM_022432, NM_001122766, NM_001122765, BC021439,
Species
mouse
UniGene ID
Mm.272443
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.