mouse SIGLEC1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Siglec1.
shAAV-271984
AAV-m-SIGLEC1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Siglec1 (sialic acid binding Ig-like lectin 1, sialoadhesin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Cd169; Siglec-1; Sn
Description (Vector)
Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid (By similarity). Binds to SPN/CD43 on T-cells (By similarity). May play a role in hemopoiesis.
Gene ID
20612
Gene Name (Vector)
sialic acid binding Ig-like lectin 1, sialoadhesin
Gene Symbol
Siglec1
ORF Size (aa)
5088
ORF Size (bp)
5088 bp
RefSeq ID
NM_011426
RefSeq Synonyms
NM_011426, BC141336, BC141335,
Species
mouse
UniGene ID
Mm.1374
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.