mouse SI shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Pmel.
shAAV-271971
AAV-m-SI-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Pmel (premelanosome protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
D10H12S53E; D12S53Eh; gp100; gp87; Pmel17; Si; Silv
Description (Vector)
Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.
Gene ID
20431
Gene Name (Vector)
premelanosome protein
Gene Symbol
Pmel
ORF Size (aa)
1881
ORF Size (bp)
1881 bp
RefSeq ID
NM_021882
RefSeq Synonyms
NM_021882, BC082555,
Species
mouse
UniGene ID
Mm.16756
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.