mouse SH3PXD2B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Sh3pxd2b.
shAAV-271918
AAV-m-SH3PXD2B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Sh3pxd2b (SH3 and PX domains 2B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
fad49; G431001E03Rik; TSK4
Description (Vector)
Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation (By similarity).
Gene ID
268396
Gene Name (Vector)
SH3 and PX domains 2B
Gene Symbol
Sh3pxd2b
ORF Size (aa)
2727
ORF Size (bp)
2727 bp
RefSeq ID
NM_177364
RefSeq Synonyms
NM_177364, BC141306,
Species
mouse
UniGene ID
Mm.227616
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.