mouse SEMA6A shRNA silencing AAV

Name 
AAV-m-SEMA6A-shRNA
Cat No 
shAAV-271598
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Sema6a.

shAAV-271598
AAV-m-SEMA6A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Sema6a (sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A730020P05Rik; AI851735; Sema6A-1; Semaq; VIa
Description (Vector)
Cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling. Required for normal granule cell migration in the developing cerebellum. Promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the developing central nervous system. Can act as repulsive axon guidance cue. Has repulsive action towards migrating granular neurons. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation (By similarity).
Gene ID
20358
Gene Name (Vector)
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
Gene Symbol
Sema6a
ORF Size (aa)
2931
ORF Size (bp)
2931 bp
RefSeq ID
NM_018744
RefSeq Synonyms
NM_018744, NM_001311097, BC062979, BC059238,
Species
mouse
UniGene ID
Mm.40909

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.