mouse RP2H shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Rp2.
shAAV-270817
AAV-m-RP2H-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Rp2 (retinitis pigmentosa 2 homolog). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI662636; Rp2h
Description (Vector)
Acts as a GTPase-activating protein (GAP) involved in trafficking between the Golgi and the ciliary membrane. Involved in localization of proteins, such as NPHP3, to the cilium membrane by inducing hydrolysis of GTP ARL3, leading to the release of UNC119 (or UNC119B). Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor towards ADP-ribosylation factor-like proteins.
Gene ID
19889
Gene Name (Vector)
retinitis pigmentosa 2 homolog
Gene Symbol
Rp2
ORF Size (aa)
1044
ORF Size (bp)
1044 bp
RefSeq ID
NM_133669
RefSeq Synonyms
NM_133669, NM_001290644, NM_001290643, BC049698,
Species
mouse
UniGene ID
Mm.288141
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.