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mouse RORC shRNA silencing AAV

Name 
AAV-m-RORC-shRNA
Cat No 
shAAV-270792
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Rorc.

shAAV-270792
AAV-m-RORC-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Rorc (RAR-related orphan receptor gamma). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
81
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Nr1f3; RORgamma; Thor; TOR
Description (Vector)
Possible nuclear receptor for hydroxycholesterols, the binding of which strongly promotes coactivators recruitment. Essential for thymopoiesis and the development of several secondary lymphoid tissues, including lymph nodes. Involved in lineage specification of uncommitted CD4(+) T-helper cells into Th17 cells. Regulate the expression of several components of the circadian clock.
Gene ID
19885
Gene Name (Vector)
RAR-related orphan receptor gamma
Gene Symbol
Rorc
ORF Size (aa)
1551
ORF Size (bp)
1551 bp
RefSeq ID
NM_011281
RefSeq Synonyms
NM_011281, NM_001293734, BC014804,
Species
mouse
UniGene ID
Mm.4372

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.