mouse RMI1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Rmi1.
shAAV-270628
AAV-m-RMI1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Rmi1 (RecQ mediated genome instability 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4932432N11Rik; C79893
Description (Vector)
Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
Gene ID
74386
Gene Name (Vector)
RecQ mediated genome instability 1
Gene Symbol
Rmi1
ORF Size (aa)
1851
ORF Size (bp)
1851 bp
RefSeq ID
NM_028904
RefSeq Synonyms
NM_028904, NM_001168248, BC037694,
Species
mouse
UniGene ID
Mm.85289
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.