mouse RECK shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Reck.
shAAV-270359
AAV-m-RECK-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Reck (reversion-inducing-cysteine-rich protein with kazal motifs). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
mRECK; St15
Description (Vector)
Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.
Gene ID
53614
Gene Name (Vector)
reversion-inducing-cysteine-rich protein with kazal motifs
Gene Symbol
Reck
ORF Size (aa)
2916
ORF Size (bp)
2916 bp
RefSeq ID
NM_016678
RefSeq Synonyms
NM_016678, BC138065, BC132197,
Species
mouse
UniGene ID
Mm.331573
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.