human HARS2 Over-expression AAV

Name
AAV-h-HARS2

Cat No
AAV-210787

Availability
4-5 weeks

This is an AAV expressing Human HARS2.

AAV-210787

AAV-h-HARS2

Ready-to-use AAV expressing Human HARS2 (histidyl-tRNA synthetase 2, mitochondrial). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HARSL; HARSR; HO3; PRLTS2

Description (Vector)

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes share a bidirectional promoter.

Gene ID

23438

Gene Name (Vector)

histidyl-tRNA synthetase 2, mitochondrial

Gene Symbol

HARS2

HGNC ID

HGNC:4817

ORF Size (aa)

1521

ORF Size (bp)

1521 bp

RefSeq ID

NM_012208

RefSeq Synonyms

NM_012208, NM_001278732, NM_001278731, BC014982, BC007680,

Species

human

UniGene ID

Hs.432560

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.