human HAP1 Over-expression AAV

Name 
AAV-h-HAP1
Cat No 
AAV-210778
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HAP1.

AAV-210778
AAV-h-HAP1

Ready-to-use AAV expressing Human HAP1 (huntingtin associated protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HAP2; hHLP1; HIP5; HLP
Description (Vector)
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene ID
9001
Gene Name (Vector)
huntingtin associated protein 1
Gene Symbol
HAP1
HGNC ID
HGNC:4812
ORF Size (aa)
2016
ORF Size (bp)
2016 bp
RefSeq ID
NM_001079870
RefSeq Synonyms
NM_177977, NM_001079871, NM_001079870, BC156728,
Species
human
UniGene ID
Hs.158300

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.