mouse PTPN6 shRNA silencing AAV

Name 
AAV-m-PTPN6-shRNA
Cat No 
shAAV-269806
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ptpn6.

shAAV-269806
AAV-m-PTPN6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ptpn6 (protein tyrosine phosphatase, non-receptor type 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
70Z-SHP; hcp; Hcph; me; Ptp1C; PTPTY-42; SH-PTP1; SHP-1
Description (Vector)
Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
Gene ID
15170
Gene Name (Vector)
protein tyrosine phosphatase, non-receptor type 6
Gene Symbol
Ptpn6
ORF Size (aa)
1788
ORF Size (bp)
1788 bp
RefSeq ID
NM_013545
RefSeq Synonyms
NM_013545, NM_001077705, BC012660,
Species
mouse
UniGene ID
Mm.271799

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.