human GZMK Over-expression AAV

Name 
AAV-h-GZMK
Cat No 
AAV-210720
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GZMK.

AAV-210720
AAV-h-GZMK

Ready-to-use AAV expressing Human GZMK (granzyme K). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
TRYP2
Description (Vector)
GZMK product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.
Gene ID
3003
Gene Name (Vector)
granzyme K
Gene Symbol
GZMK
HGNC ID
HGNC:4711
ORF Size (aa)
795
ORF Size (bp)
795 bp
RefSeq ID
NM_002104
RefSeq Synonyms
NM_002104, BC035802,
Species
human
UniGene ID
Hs.277937

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.