human GYPB Over-expression AAV

Name 
AAV-h-GYPB
Cat No 
AAV-210705
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GYPB.

AAV-210705
AAV-h-GYPB

Ready-to-use AAV expressing Human GYPB (glycophorin B (MNS blood group)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD235b; GPB; GYP; MNS; PAS-3; SS
Description (Vector)
Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB.
Gene ID
2994
Gene Name (Vector)
glycophorin B (MNS blood group)
Gene Symbol
GYPB
HGNC ID
HGNC:4703
ORF Size (aa)
276
RefSeq ID
NM_002100
RefSeq Synonyms
NM_002100, NM_001304382, BC121078, BC121077, BC069310,
Species
human
UniGene ID
Hs.654368

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.