mouse PRDM16 shRNA silencing AAV

Name
AAV-m-PRDM16-shRNA

Cat No
shAAV-269306

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Prdm16.

shAAV-269306

AAV-m-PRDM16-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Prdm16 (PR domain containing 16). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

5730557K01Rik; csp1; mel1

Description (Vector)

Binds DNA and functions as a transcriptional regulator. Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism. Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells. Functions also as a repressor of TGF-beta signaling. Isoform 4 may regulate granulocytes differentiation.

Gene ID

70673

Gene Name (Vector)

PR domain containing 16

Gene Symbol

Prdm16

ORF Size (aa)

3537

ORF Size (bp)

3537 bp

RefSeq ID

NM_027504

RefSeq Synonyms

NM_027504, NM_001291029, NM_001291026, NM_001177995, BC059838,

Species

mouse

UniGene ID

Mm.257785

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.