mouse PPP2R5B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Ppp2r5b.
shAAV-269243
AAV-m-PPP2R5B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Ppp2r5b (protein phosphatase 2, regulatory subunit B’, beta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
B'beta; BC026670
Description (Vector)
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The phosphorylated form mediates the interaction between AKT1 and PP2A phosphatase leading to dephosphorylation of AKT1 on the 'Thr-308' and 'Ser-373' residues.
Gene ID
225849
Gene Name (Vector)
protein phosphatase 2, regulatory subunit B', beta
Gene Symbol
Ppp2r5b
ORF Size (aa)
1494
ORF Size (bp)
1494 bp
RefSeq ID
NM_198168
RefSeq Synonyms
NM_198168, BC058977,
Species
mouse
UniGene ID
Mm.118076
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.