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rat PPP2R5B shRNA silencing AAV

Name 
AAV-r-PPP2R5B-shRNA
Cat No 
shAAV-293135
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Rat Ppp2r5b.

shAAV-293135
AAV-r-PPP2R5B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Ppp2r5b (protein phosphatase 2, regulatory subunit B’, beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The phosphorylated form mediates the interaction between AKT1 and PP2A phosphatase leading to dephosphorylation of AKT1 on the 'Thr-308' and 'Ser-373' residues.
Gene ID
309179
Gene Name (Vector)
protein phosphatase 2, regulatory subunit B', beta
Gene Symbol
Ppp2r5b
ORF Size (aa)
1494
ORF Size (bp)
1494 bp
RefSeq ID
NM_181379
RefSeq Synonyms
NM_181379, BC090324,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.