human GUSB Over-expression AAV

Name 
AAV-h-GUSB
Cat No 
AAV-210699
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GUSB.

AAV-210699
AAV-h-GUSB

Ready-to-use AAV expressing Human GUSB (glucuronidase beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BG; MPS7
Description (Vector)
GUSB encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. There are many pseudogenes of this locus in the human genome.
Gene ID
2990
Gene Name (Vector)
glucuronidase beta
Gene Symbol
GUSB
HGNC ID
HGNC:4696
ORF Size (aa)
1956
ORF Size (bp)
1956 bp
RefSeq ID
NM_000181
RefSeq Synonyms
NM_001293105, NM_001293104, NM_001284290, NM_000181, BC014142,
Species
human
UniGene ID
Hs.255230

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.