human GTF2H1 Over-expression AAV

Name 
AAV-h-GTF2H1
Cat No 
AAV-210639
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GTF2H1.

AAV-210639
AAV-h-GTF2H1

Ready-to-use AAV expressing Human GTF2H1 (general transcription factor IIH subunit 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
basic transcription factor 2 62 kDa subunit; BTF2; BTF2 p62; epididymis secretory sperm binding protein; general transcription factor IIH polypeptide 1; general transcription factor IIH subunit 1; general transcription factor IIH, polypeptide 1, 62kDa; P62; TFB1; TFIIH; TFIIH basal transcription factor complex p62 subunit
Description (eCommerce)
GTF2H1 (general transcription factor IIH, polypeptide 1, 62kDa) is a component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA. When complexed to CAK, GTF2H1 is involved in RNA transcription by RNA polymerase II [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P32780].
Gene ID
2965
Gene Name (eCommerce)
general transcription factor IIH subunit 1
Gene Name (Vector)
general transcription factor IIH subunit 1
Gene Symbol
GTF2H1
HGNC ID
HGNC:4655
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1647
ORF Size (bp)
1647 bp
Protein Name (eCommerce)
General transcription factor IIH subunit 1
RefSeq ID
NM_005316
RefSeq Synonyms
NM_005316, NM_001142307, BC004452, BC000365,
Research Areas
Cancer,DNA Damage/Repair,Epigenetic Regulation of Gene Expression,Gene Expression,Host-Virus Interactions,mRNA Processing,RNA Processing,Transcription Factor/Regulator,Viral Carcinogenesis
Research Areas (Faceted)
cancer,cell_biology,genetics,transcription_translation,infectious_disease
Species
human
Target Sentence
GTF2H1 (general transcription factor IIH, polypeptide 1, 62kDa) is a component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA. When complexed to CAK, GTF2H1 is involved in RNA transcription by RNA polymerase II [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P32780].
UniGene ID
Hs.577202
UniProt ID (eCommerce)
P32780

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.