mouse PHF21A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Phf21a.
shAAV-268535
AAV-m-PHF21A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Phf21a (PHD finger protein 21A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
80kDa; Bhc; Bhc80; D030065N23Rik; PFTF1
Description (Vector)
Component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it may act as a scaffold. Inhibits KDM1A-mediated demethylation of 'Lys-4' of histone H3 in vitro, suggesting a role in demethylation regulation.
Gene ID
192285
Gene Name (Vector)
PHD finger protein 21A
Gene Symbol
Phf21a
ORF Size (aa)
1671
ORF Size (bp)
1671 bp
RefSeq ID
NM_138755
RefSeq Synonyms
NM_138755, NM_001346704, NM_001109691, NM_001109690, BC019181,
Species
mouse
UniGene ID
Mm.450689
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.