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mouse PDE5A shRNA silencing AAV

Name 
AAV-m-PDE5A-shRNA
Cat No 
shAAV-268296
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Pde5a.

shAAV-268296
AAV-m-PDE5A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Pde5a (phosphodiesterase 5A, cGMP-specific). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Cgbpde; Cn5n; Pde5; Pde5a1; PDE5a2
Description (Vector)
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP.
Gene ID
242202
Gene Name (Vector)
phosphodiesterase 5A, cGMP-specific
Gene Symbol
Pde5a
ORF Size (aa)
2598
ORF Size (bp)
2598 bp
RefSeq ID
NM_153422
RefSeq Synonyms
NM_153422, BC120486, BC119137,
Species
mouse
UniGene ID
Mm.443704

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.