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mouse PDCD1LG2 shRNA silencing AAV

Name 
AAV-m-PDCD1LG2-shRNA
Cat No 
shAAV-268265
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Pdcd1lg2.

shAAV-268265
AAV-m-PDCD1LG2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Pdcd1lg2 (programmed cell death 1 ligand 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
B7-DC; Btdc; F730015O22Rik; PD-L2
Description (Vector)
Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).
Gene ID
58205
Gene Name (Vector)
programmed cell death 1 ligand 2
Gene Symbol
Pdcd1lg2
ORF Size (aa)
744
ORF Size (bp)
744 bp
RefSeq ID
NM_021396
RefSeq Synonyms
NM_021396, BC104139, BC104138,
Species
mouse
UniGene ID
Mm.116737

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.