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human PDCD1LG2 shRNA silencing AAV

Name 
AAV-h-PDCD1LG2-shRNA
Cat No 
shAAV-218436
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PDCD1LG2.

shAAV-218436
AAV-h-PDCD1LG2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PDCD1LG2 (programmed cell death 1 ligand 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
B7 dendritic cell molecule;B7DC;B7-DC;bA574F11.2;Btdc;butyrophilin B7-DC;CD antigen CD273;CD273;PD-1 ligand 2;PD-1-ligand 2;PDCD1 ligand 2;PDCD1L2;PDL2;PD-L2;programmed cell death 1 ligand 2;programmed death ligand 2
Description (eCommerce)
Programmed cell death 1 ligand 2 (PD-L2) is involved in the regulation of activated T cell proliferation, interferon-gamma production, and interleukin-10 production. PD-L2 is a member of the B7 family of cell surface ligands and acts through binding of PD-1. [taken from NCBI Entrez Gene (Gene ID: 80380)].
Gene ID
80380
Gene Name (eCommerce)
programmed cell death 1 ligand 2
Gene Name (Vector)
programmed cell death 1 ligand 2
Gene Symbol
PDCD1LG2
HGNC ID
HGNC:18731
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
822
ORF Size (bp)
822 bp
Protein Name (eCommerce)
Programmed cell death 1 ligand 2
RefSeq ID
NM_025239
RefSeq Synonyms
NM_025239, BC113680, BC113678, BC074766,
Research Areas
Immunology,Signal Transduction
Research Areas (Faceted)
signal_transduction,immunology
Species
human
Target Sentence
Programmed cell death 1 ligand 2 (PD-L2) is involved in the regulation of activated T cell proliferation, interferon-gamma production, and interleukin-10 production. PD-L2 is a member of the B7 family of cell surface ligands and acts through binding of PD-1. [taken from NCBI Entrez Gene (Gene ID: 80380)].
UniGene ID
Hs.617872
UniProt ID (eCommerce)
Q9BQ51

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.