mouse PAK6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Pak6.
shAAV-268019
AAV-m-PAK6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Pak6 (p21 protein (Cdc42/Rac)-activated kinase 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4732456M09
Description (Vector)
Serine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR-mediated transcription. Inhibits also ESR1-mediated transcription. May play a role in cytoskeleton regulation by interacting with IQGAP1. May protect cells from apoptosis through phosphorylation of BAD.
Gene ID
214230
Gene Name (Vector)
p21 protein (Cdc42/Rac)-activated kinase 6
Gene Symbol
Pak6
ORF Size (aa)
2049
ORF Size (bp)
2049 bp
RefSeq ID
NM_001145854
RefSeq Synonyms
NM_001145854, NM_001033254, BC150754,
Species
mouse
UniGene ID
Mm.241857
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.