human PAK6 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PAK6.
shADV-218159
Ad-h-PAK6-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PAK6 (p21 (RAC1) activated kinase 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PAK5
Description (Vector)
PAK6 encodes a member of the p21-activated kinase (PAK) family. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. PAK6 was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Gene ID
56924
Gene Name (Vector)
p21 (RAC1) activated kinase 6
Gene Symbol
PAK6
HGNC ID
HGNC:16061
ORF Size (aa)
2046
ORF Size (bp)
2046 bp
RefSeq ID
NM_020168
RefSeq Synonyms
NM_020168, NM_001276718, NM_001276717, BC035596,
Species
human
UniGene ID
Hs.513645
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.