mouse OTUD5 shRNA silencing AAV

Name 
AAV-m-OTUD5-shRNA
Cat No 
shAAV-267904
Availability
Immediate
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Otud5.

shAAV-267904
AAV-m-OTUD5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Otud5 (OTU domain containing 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AA407879; AI553596; BB114028; DUBA; DXImx46e; Sfc7
Description (Vector)
Deubiquitinating enzyme that functions as negative regulator of the innate immune system. Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production. Has peptidase activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Can also cleave 'Lys-11'-linked ubiquitin chains (in vitro).
Gene ID
54644
Gene Name (Vector)
OTU domain containing 5
Gene Symbol
Otud5
ORF Size (aa)
1701
ORF Size (bp)
1701 bp
RefSeq ID
NM_138604
RefSeq Synonyms
NM_138604, NM_001290537, NM_001290536, BC051111, BC016529,
Species
mouse
UniGene ID
Mm.142827

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.