human GRIA4 Over-expression AAV

Name 
AAV-h-GRIA4
Cat No 
AAV-210508
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GRIA4.

AAV-210508
AAV-h-GRIA4

Ready-to-use AAV expressing Human GRIA4 (glutamate ionotropic receptor AMPA type subunit 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GluA4; GLUR4; GLUR4C; GLURD
Description (Vector)
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia.
Gene ID
2893
Gene Name (Vector)
glutamate ionotropic receptor AMPA type subunit 4
Gene Symbol
GRIA4
HGNC ID
HGNC:4574
ORF Size (aa)
2709
ORF Size (bp)
2709 bp
RefSeq ID
NM_000829
RefSeq Synonyms
NM_001112812, NM_001077244, NM_001077243, NM_000829, BC167786,
Species
human
UniGene ID
Hs.503743

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.