mouse OCRL shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Ocrl.
shAAV-266316
AAV-m-OCRL-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Ocrl (oculocerebrorenal syndrome of Lowe). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
9530014D17Rik; BB143339; OCRL1
Description (Vector)
Converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate. May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes. Involved in primary cilia assembly.
Gene ID
320634
Gene Name (Vector)
oculocerebrorenal syndrome of Lowe
Gene Symbol
Ocrl
ORF Size (aa)
2703
ORF Size (bp)
2703 bp
RefSeq ID
NM_177215
RefSeq Synonyms
NM_177215, BC068146,
Species
mouse
UniGene ID
Mm.210343
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.