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mouse OAZ1 shRNA silencing AAV

Name 
AAV-m-OAZ1-shRNA
Cat No 
shAAV-266296
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Oaz1.

shAAV-266296
AAV-m-OAZ1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Oaz1 (ornithine decarboxylase antizyme 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
94
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Antizyme; AZ-1; AZ1; Oaz; ODC-Az
Description (Vector)
Binds to, and destabilizes, ornithine decarboxylase which is then degraded. Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.
Gene ID
18245
Gene Name (Vector)
ornithine decarboxylase antizyme 1
Gene Symbol
Oaz1
ORF Size (aa)
201
RefSeq ID
NM_001301034
RefSeq Synonyms
NM_008753, NM_001301034, BC094287,
Species
mouse
UniGene ID
Mm.398119

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.