mouse NIT1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Nit1.
shAAV-265791
AAV-m-NIT1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Nit1 (nitrilase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI255805; ESTM30; W57327
Description (Vector)
Plays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2 (By similarity).
Gene ID
27045
Gene Name (Vector)
nitrilase 1
Gene Symbol
Nit1
ORF Size (aa)
972
ORF Size (bp)
972 bp
RefSeq ID
NM_012049
RefSeq Synonyms
NM_012049, NM_001242580, BC021634,
Species
mouse
UniGene ID
Mm.12915
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.