mouse NCOR2 shRNA silencing AAV

Name 
AAV-m-NCOR2-shRNA
Cat No 
shAAV-265527
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ncor2.

shAAV-265527
AAV-m-NCOR2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ncor2 (nuclear receptor co-repressor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
N-CoR; SMRT; SMRTe
Description (Vector)
Transcriptional corepressor of NR4A2/NURR1 and acts through histone deacetylases (HDACs) to keep promoters of NR4A2/NURR1 target genes in a repressed deacetylated state (By similarity). Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors.
Gene ID
20602
Gene Name (Vector)
nuclear receptor co-repressor 2
Gene Symbol
Ncor2
ORF Size (aa)
7521
ORF Size (bp)
7521 bp
RefSeq ID
NM_011424
RefSeq Synonyms
NM_011424, NM_001253905, NM_001253904, BC156549,
Species
mouse
UniGene ID
Mm.278646

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.