mouse MKS1 shRNA silencing AAV

Name
AAV-m-MKS1-shRNA

Cat No
shAAV-264679

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Mks1.

shAAV-264679

AAV-m-MKS1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Mks1 (Meckel syndrome, type 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AK190930; B8d3

Description (Vector)

Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology.

Gene ID

380718

Gene Name (Vector)

Meckel syndrome, type 1

Gene Symbol

Mks1

ORF Size (aa)

1686

ORF Size (bp)

1686 bp

RefSeq ID

NM_001039684

RefSeq Synonyms

NM_001039684, BC158122, BC150995,

Species

mouse

UniGene ID

Mm.24404

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.