mouse MITF shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Mitf.
shAAV-264666
AAV-m-MITF-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Mitf (microphthalmia-associated transcription factor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BCC2; Bhlhe32; bw; Gsfbcc2; mi; vit; Vitiligo; Wh
Description (Vector)
Transcription factor for tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1) that plays a key role in melanocyte development. Binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') found in the tyrosinase promoter. Plays a critical role in the differentiation of various cell types as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
Gene ID
17342
Gene Name (Vector)
microphthalmia-associated transcription factor
Gene Symbol
Mitf
ORF Size (aa)
1260
RefSeq ID
NM_008601
RefSeq Synonyms
NM_008601, NM_001178049, NM_001113198, BC108977, BC108976,
Species
mouse
UniGene ID
Mm.454504
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.