human GOT2 Over-expression AAV

Name 
AAV-h-GOT2
Cat No 
AAV-210187
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GOT2.

AAV-210187
AAV-h-GOT2

Ready-to-use AAV expressing Human GOT2 (glutamic-oxaloacetic transaminase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
aspartate aminotransferase 2; aspartate aminotransferase, mitochondrial; aspartate transaminase 2; FABP-1; FABPpm; fatty acid-binding protein; glutamate oxaloacetate transaminase 2; glutamic-oxaloacetic transaminase 2, mitochondrial; KAT4; KATIV; KYAT4; kynurenine aminotransferase 4; kynurenine aminotransferase IV; kynurenine--oxoglutarate transaminase 4; kynurenine--oxoglutarate transaminase IV; mAspAT; mitAAT; plasma membrane-associated fatty acid-binding protein; transaminase A
Description (eCommerce)
Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology [taken from NCBI Entrez Gene (Gene ID: 2806)].
Description (Vector)
Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.
Gene ID
2806
Gene Name (eCommerce)
glutamic-oxaloacetic transaminase 2
Gene Name (Vector)
glutamic-oxaloacetic transaminase 2
Gene Symbol
GOT2
HGNC ID
HGNC:4433
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1293
ORF Size (bp)
1293 bp
Protein Name (eCommerce)
Aspartate aminotransferase, mitochondrial
RefSeq ID
NM_002080
RefSeq Synonyms
NM_002080, NM_001286220, BC000525,
Research Areas
Metabolism/Metabolic Process,Mitochondrion
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology [taken from NCBI Entrez Gene (Gene ID: 2806)].
UniGene ID
Hs.599470
UniProt ID (eCommerce)
P00505

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.