mouse KCNJ11 shRNA silencing AAV

Name 
AAV-m-KCNJ11-shRNA
Cat No 
shAAV-262651
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Kcnj11.

shAAV-262651
AAV-m-KCNJ11-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Kcnj11 (potassium inwardly rectifying channel, subfamily J, member 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Kir6.2; mBIR
Description (Vector)
This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium (By similarity). Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.
Gene ID
16514
Gene Name (Vector)
potassium inwardly rectifying channel, subfamily J, member 11
Gene Symbol
Kcnj11
ORF Size (aa)
1173
RefSeq ID
NM_010602
RefSeq Synonyms
NM_010602, NM_001204411, BC057006, BC052731,
Species
mouse
UniGene ID
Mm.333863

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.