human KCNK18 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human KCNK18.
shAAV-212741
AAV-h-KCNK18-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human KCNK18 (potassium two pore domain channel subfamily K member 18). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
K2p18.1; MGR13; TRESK; TRESK-2; TRESK2; TRIK
Description (Vector)
Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains and the encoded protein functions as an outward rectifying potassium channel. A mutation in this gene has been found to be associated with migraine with aura.
Gene ID
338567
Gene Name (Vector)
potassium two pore domain channel subfamily K member 18
Gene Symbol
KCNK18
HGNC ID
HGNC:19439
ORF Size (aa)
1152
ORF Size (bp)
1152 bp
RefSeq ID
NM_181840
RefSeq Synonyms
NM_181840, BC152979, BC148337,
Species
human
UniGene ID
Hs.449650
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.