mouse ILK shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Ilk.
shAAV-262206
AAV-m-ILK-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Ilk (integrin linked kinase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AA511515; ESTM24
Description (Vector)
Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.
Gene ID
16202
Gene Name (Vector)
integrin linked kinase
Gene Symbol
Ilk
ORF Size (aa)
1359
ORF Size (bp)
1359 bp
RefSeq ID
NM_010562
RefSeq Synonyms
NM_010562, NM_001161724, BC003737,
Species
mouse
UniGene ID
Mm.274846
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.