mouse IL16 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Il16.
shAAV-262107
AAV-m-IL16-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Il16 (interleukin 16). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
mKIAA4048
Description (Vector)
Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4|Function: Isoform 1 may act as a scaffolding protein that anchors ion channels in the membrane|Function: Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.
Gene ID
16170
Gene Name (Vector)
interleukin 16
Gene Symbol
Il16
ORF Size (aa)
3969
ORF Size (bp)
3969 bp
RefSeq ID
NM_010551
RefSeq Synonyms
NM_010551, BC058709,
Species
mouse
UniGene ID
Mm.10137
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.