mouse IGF2R shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Igf2r.
shAAV-261968
AAV-m-IGF2R-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Igf2r (insulin-like growth factor 2 receptor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI661837; CD222; CI-MPR; M6P/IGF2R; Mpr300
Description (Vector)
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
Gene ID
16004
Gene Name (Vector)
insulin-like growth factor 2 receptor
Gene Symbol
Igf2r
ORF Size (aa)
7452
ORF Size (bp)
7452 bp
RefSeq ID
NM_010515
RefSeq Synonyms
NM_010515, BC171973, BC150817,
Species
mouse
UniGene ID
Mm.26553
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.