human GJC2 Over-expression AAV

Name 
AAV-h-GJC2
Cat No 
AAV-209935
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GJC2.

AAV-209935
AAV-h-GJC2

Ready-to-use AAV expressing Human GJC2 (gap junction protein gamma 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CX46.6; Cx47; GJA12; HLD2; LMPH1C; PMLDAR; SPG44
Description (Vector)
GJC2 encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. GJC2 plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.
Gene ID
57165
Gene Name (Vector)
gap junction protein gamma 2
Gene Symbol
GJC2
HGNC ID
HGNC:17494
ORF Size (aa)
1320
ORF Size (bp)
1320 bp
RefSeq ID
NM_020435
RefSeq Synonyms
NM_020435, BC089439,
Species
human
UniGene ID
Hs.100072

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.