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mouse GPX4 shRNA silencing AAV

Name 
AAV-m-GPX4-shRNA
Cat No 
shAAV-260717
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Gpx4.

shAAV-260717
AAV-m-GPX4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Gpx4 (glutathione peroxidase 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GPx-4; GSHPx-4; mtPHGPx; PHGPx; snGPx
Description (Vector)
Protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage (By similarity).
Gene ID
625249
Gene Name (Vector)
glutathione peroxidase 4
Gene Symbol
Gpx4
ORF Size (aa)
513
RefSeq ID
NM_001037741
RefSeq Synonyms
NM_008162, NM_001037741, BC106147,
Species
mouse
UniGene ID
Mm.359573

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.