mouse GPR143 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Gpr143.
shAAV-260585
AAV-m-GPR143-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Gpr143 (G protein-coupled receptor 143). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Oa1
Description (Vector)
Receptor for tyrosine, L-DOPA and dopamine. After binding to L-DOPA, stimulates Ca(2+) influx into the cytoplasm, increases secretion of the neurotrophic factor SERPINF1 and relocalizes beta arrestin at the plasma membrane; this ligand-dependent signaling occurs through a G(q)-mediated pathway in melanocytic cells. Its activity is mediated by G proteins which activate the phosphoinositide signaling pathway. Plays also a role as an intracellular G protein-coupled receptor involved in melanosome biogenesis, organization and transport.
Gene ID
18241
Gene Name (Vector)
G protein-coupled receptor 143
Gene Symbol
Gpr143
ORF Size (aa)
1218
ORF Size (bp)
1218 bp
RefSeq ID
NM_010951
RefSeq Synonyms
NM_010951, BC137813, BC119384,
Species
mouse
UniGene ID
Mm.5157
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.