human GPR143 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GPR143.
shAAV-210291
AAV-h-GPR143-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GPR143 (G protein-coupled receptor 143). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
NYS6; OA1
Description (Vector)
GPR143 encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in this gene cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y.
Gene ID
4935
Gene Name (Vector)
G protein-coupled receptor 143
Gene Symbol
GPR143
HGNC ID
HGNC:20145
ORF Size (aa)
1275
ORF Size (bp)
1275 bp
RefSeq ID
NM_000273
RefSeq Synonyms
NM_000273, BC068977,
Species
human
UniGene ID
Hs.74124
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.