mouse GNE shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Gne.
shAAV-260406
AAV-m-GNE-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Gne (glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2310066H07Rik; DMRV; GLCNE; IBM2; NM; Uae1
Description (Vector)
Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Plays an essential role in early development (By similarity). Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells.
Gene ID
50798
Gene Name (Vector)
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
Gene Symbol
Gne
ORF Size (aa)
2169
ORF Size (bp)
2169 bp
RefSeq ID
NM_015828
RefSeq Synonyms
NM_015828, NM_001190414, BC051254, BC015277,
Species
mouse
UniGene ID
Mm.256718
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.