mouse GLO1 shRNA silencing AAV

Name 
AAV-m-GLO1-shRNA
Cat No 
shAAV-260185
Availability
Immediate
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Glo1.

shAAV-260185
AAV-m-GLO1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Glo1 (glyoxalase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
0610009E22Rik; 1110008E19Rik; 2510049H23Rik; AW550643; Glo-1; Glo-1r; Glo-1s; Glo1-r; Glo1-s; GLY1; Qglo
Description (Vector)
Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B.
Gene ID
109801
Gene Name (Vector)
glyoxalase 1
Gene Symbol
Glo1
ORF Size (aa)
555
ORF Size (bp)
555 bp
RefSeq ID
NM_025374
RefSeq Synonyms
NM_025374, NM_001113560, BC081432, BC024663,
Species
mouse
UniGene ID
Mm.261984

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.