human GFRA4 Over-expression AAV

Name
AAV-h-GFRA4

Cat No
AAV-209835

Availability
4-5 weeks

This is an AAV expressing Human GFRA4.

AAV-209835

AAV-h-GFRA4

Ready-to-use AAV expressing Human GFRA4 (GDNF family receptor alpha 4). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

GFRA4 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for RET-associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene ID

64096

Gene Name (Vector)

GDNF family receptor alpha 4

Gene Symbol

GFRA4

HGNC ID

HGNC:13821

ORF Size (aa)

897

ORF Size (bp)

897 bp

RefSeq ID

NM_022139

RefSeq Synonyms

NM_145762, NM_022139, BC172567, BC172271,

Species

human

UniGene ID

Hs.302025

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.