mouse GAN shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Gan.
shAAV-259882
AAV-m-GAN-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Gan (giant axonal neuropathy). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
A330045G18; gigaxonin
Description (Vector)
Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. Substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival.
Gene ID
209239
Gene Name (Vector)
giant axonal neuropathy
Gene Symbol
Gan
ORF Size (aa)
1794
ORF Size (bp)
1794 bp
RefSeq ID
NM_001081151
RefSeq Synonyms
NM_001081151, BC165989,
Species
mouse
UniGene ID
Mm.132992
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.