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mouse GALC shRNA silencing AAV

Name 
AAV-m-GALC-shRNA
Cat No 
shAAV-259838
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Galc.

shAAV-259838
AAV-m-GALC-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Galc (galactosylceramidase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2310068B06Rik; A930008M05Rik; AW212969; AW413532; Gacy; twi; twitcher
Description (Vector)
Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon.
Gene ID
14420
Gene Name (Vector)
galactosylceramidase
Gene Symbol
Galc
ORF Size (aa)
2007
ORF Size (bp)
2007 bp
RefSeq ID
NM_008079
RefSeq Synonyms
NM_008079, BC086671,
Species
mouse
UniGene ID
Mm.5120

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.