human GALC shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GALC.
shAAV-209571
AAV-h-GALC-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GALC (galactosylceramidase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
GALC encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID
2581
Gene Name (Vector)
galactosylceramidase
Gene Symbol
GALC
HGNC ID
HGNC:4115
ORF Size (aa)
2010
ORF Size (bp)
2010 bp
RefSeq ID
NM_000153
RefSeq Synonyms
NM_001201402, NM_001201401, NM_000153, BC036518,
Species
human
UniGene ID
Hs.513439
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.