mouse FNBP1L shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Fnbp1l.
shAAV-259521
AAV-m-FNBP1L-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Fnbp1l (formin binding protein 1-like). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2610318I01Rik; AW548221; toca-1; TOCA1
Description (Vector)
Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Essential for autophagy of intracellular bacterial pathogens.
Gene ID
214459
Gene Name (Vector)
formin binding protein 1-like
Gene Symbol
Fnbp1l
ORF Size (aa)
1116
ORF Size (bp)
1116 bp
RefSeq ID
NM_153118
RefSeq Synonyms
NM_153118, NM_001114665, BC034510,
Species
mouse
UniGene ID
Mm.470230
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.